| Literatur, Patente |
| |
O'Shaugnessy: "Monograph on Cannabis Medicine" 1839 Abhandlung
zur medizinischen Verwendung von Cannabis.. |
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"New Billion-Dollar Crop" Popular Mechanics 2.1938 die erste
vollautomatische Hanf-Schälmaschine.. |
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Krejci: "Hemp as a medicament" Dissertation, Faculty of
Natural Sciences, Brno, Tschechoslowakei 1950 |
| |
Kabilek: "Hemp as a medicament" Acta Univ Palacki Olomuc
Tom VI 6 1-81 1955 |
| |
Ferenczy: "Antibacterial substances in seeds" Nature 178
639-640 1956 |
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Kabilek: "Hanf (Cannabis sativa) - Antibiotisches Heilmittel.
1. Mitteilung: Hanf in der Alt-und Volksmedizin" Pharmazie 12,7
439-443 7.1957 |
| |
Krejci: "Hanf (Cannabis sativa) - Antibiotisches Heilmittel.
2. Mitteilung: Methodik und Ergebnisse der bakteriologischen Untersuchungen
und vorläufige klinische Erfahrungen" Pharmazie 13,3 155-166
3.1958 |
| |
Ferenczy, Gracza, Jakobey: "An antibacterial preparatum from
hemp (Cannabis sativa L.)" Naturwissenschaften 45 188 1958 |
| |
Krejci, Horak, Santavy: "Hanf (Cannabis sativa) - Antibiotisches
Heilmittel 3. Mitteilung: Isolierung und Konstitution zweier aus Cannabis
sativa gewonnener Säure" Pharmazie 14,6 349-355 6.1959 |
| |
Schultz, Hafner: "Zur Kenntnis eines sedativen und antibakteriellen
Wirkstoffes aus deutschem Faserhanf (Cannabis sativa)" Z Naturforschung
14b 98-100 1959 |
| |
Kabelík, Krejcí, Santavy: "Cannabis as a medicament"
Bull Narc 12 5-23 1960 |
| |
Radosevic, Kupinic, Grlic: "Antibiotic activity of various types
of cannabis resin" Nature 195 1007-1009 8.9.1962 |
| |
Girlic, Tomic: "Examination of cannabis resin by means of ferric
chloride test" Experientia 19 267-268 15.5.1963 |
| |
"Cancer Curb Is Studied" Washington Post 18.8.1974 Studie
am Medical College Virginia NIH-gefördert.. THC verlangsamt Krebswachstum
bei Mäusen.. Lungenkrebs, Brustkrebs, Virusausgelöste Leukämie..
bis 36% Lebensverlängerung.. |
| |
Munson, Harris, Friedman, Dewey, Carchman: "Antineoplastic activity
of cannabinoids" J Natl Cancer Inst 55,3 597-602 9.1975 orales
THC hemmt Lewis-Lungenadenokarzinom.. dosisabhängiger Effekt nach
10 Tagen Behandlung.. kleinerer Primärtumor durch 20 Tage Behandlung..
mittlere Lebenszeit +36% bei 100mg/kg.. kein Effekt bei L1210 murine
leukemia.. hemmt Friend Leukämievirus um 71%.. |
| |
Carchman, Harris, Munson: "The inhibition of DNA synthesis by
cannabinoids" Cancer Res 36,1 95-100 1.1976 |
| |
Van Klingeren, Ten Ham: "Antibacterial activity of Delta9-tetrahydrocannabinol
and cannabidiol" Antonie Van Leeuwenhoek 42,1-2 9-12 1976 |
| |
Friedman: "In vivo effects of cannabinoids on macromolecular
biosynthesis in Lewis lung carcinomas" J Natl Cancer Inst 56,3
655-658 3.1976 |
| |
Friedman: "In vivo effects of cannabinoids on macromolecular
biosynthesis in Lewis lung carcinomas" Cancer Biochem Biophys 2,2
51-54 1977 Cannabinoide zur Lebensverlängerung bei Lewis Lungentumoren,
Reduzierung Tumorgröße.. |
| |
Ottersen, Rosenqvist, Turner, El-Feraly: "The crystal and molecular
structure of cannabidiol" Acta Chem Scand B31,9 807-812 1977 Kristallstruktur.. |
| |
Tucker, Friedman: "Effects of cannabinoids on L1210 murine leukemia.
1. Inhibition of DNA synthesis" Cancer Biochem Biophys 2,2 51-54
1977 |
| |
Fournier et al: "Bacteriostatic activity of Cannabis-sativa essential
oil" Annales Pharmaceutiques Francaises 1978 |
| |
Tucker, Friedman: "Effects of cannabinoids on L1210 murine leukemia.
III. Inhibition of respiration" Res Commun Chem Pathol Pharmacol
23,2 327-332 2.1979 |
| |
Turner, Elsohly, Boeren: "Constituents of Cannabis sativa L.
XVII. A review of the natural constituents" J Nat Prod 43,2 169-234
1980 |
| |
Cunha, Carlini, Pereira, Ramos, Pimentel, Gagliardi, Sanvito, Lander,
Mechoulam: "Chronic administration of cannabidiol to healthy volunteers
and epileptic patients" Pharmacology 21,3 175-185 1980 |
| |
Consroe, Kudraya, Schmitz: "Acute and chronic antiepileptic drug
effects in audiogenic seizure-susceptible rats" Exp Neurology 70,3
626-637 12.1980 |
| |
Carlini, Cunha: "Hypnotic and antiepileptic effects of cannabidiol"
J Clin Pharmacol 21 417S-427S 1981 |
| |
Karler, Turkanis: "The cannabinoids as potential antiepileptics"
J Clin Pharmacol 21,8-9 Suppl 437S-448S 1981 |
| |
Consroe, Martin, Singh: "Antiepileptic potential of cannabidiol
analogs" J Clin Pharmacol 21,8-9 Suppl 428S-436S 1981 |
| |
Eisohly, Turner, Clark, Eisohly: "Synthesis and antimicrobial
activities of certain cannabichromene and cannabigerol related compounds"
J Pharm Sci 71,12 1319-1323 1082 |
| |
Murison, Chubb, Maeda, Gemmell, Huberman: "Cannabinoids induce
incomplete maturation of cultured human leukemia cells" Proc Natl
Acad Sci 84:5414-5418 1987 |
| |
Wasim, Haq, Ashraf: "Antimicrobial studies of the leaf of Cannabis
sativa L" Pak J Pharm Sci 8,1 29-38 1995 |
| |
Klein, Friedman, Specter: "Marijuana, immunity and infection"
J Neuroimmunol 83,1-2 102-115 15.3.1998 |
| |
Baek, Kim, Kwag, Choi, Jung, Han: "Boron trifluoride etherate
on silica-A modified Lewis acid reagent (VII). Antitumor activity of
cannabigerol against human oral epitheloid carcinoma cells" Arch
Pharm Res 21,3 353-356 6.1998 |
| |
Melck, De Petrocellis, Orlando, Bisogno, Laezza, Bifulco, Di Marzo:
"Suppression of nerve growth factor Trk receptors and prolactin
receptors by endocannabinoids leads to inhibition of human breast and
prostate cancer cell proliferation" Eur J Biochem 254,3 634-642
15.6.1998 |
| |
Jacobsson, Wallin, Fowler: "Inhibition of rat C6 glioma cell
proliferation by endogenous and synthetic cannabinoids. Relative involvement
of cannabinoid and vanilloid receptors" Proc Natl Acad Sci USA
95,14 8375-8380 7.7.1998 |
| |
De Petrocellis, Melck, Palmisano, Bisogno, Laezza, Bifulco, Di Marzo:
"The endogenous cannabinoid anandamide inhibits human breast cancer
cell proliferation" Proc Natl Acad Sci USA 95,14 8375-8380 7.7.1998 |
| |
Sánchez, Galve-Roperh, Canova, Brachet, Guzman: "Delta9-tetrahydrocannabinol
induces apoptosis in C6 glioma cells" FEBS Lett 436,1 6-10 25.9.1998
Cannabis gg. Gliomzellen.. |
| |
Ruiz, Miguel, Díaz-Laviada: "Delta9-tetrahydrocannabinol
induces apoptosis in human prostate PC-3 cells via a receptor-independent
mechanism" FEBS Lett 458,3 400-404 24.9.1999 |
| |
De Petrocellis, Melck, Bisogno, Di Marzo: "Endocannabinoids and
fatty acid amides in cancer, inflammation and related disorders"
Endocrinology 141,1 118-126 1.2000 |
| |
Galve-Roperh, Sánchez, Cortés, Gómez del Pulgar,
Izquierdo, Guzman: "Anti-tumoral action of cannabinoids: involvement
of sustained ceramide accumulation and extracellular signal-regulated
kinase activation" Nat Med 6,3 313-319 3.2000 THC lässt Hirntumore
(Gliome) bei Ratten schrumpfen.. |
| |
Di Marzo, Melck, De Petrocellis, Bisogno: "Cannabimimetic fatty
acid derivatives in cancer and inflammation" Prostaglandins Other
Lipid Mediat 61,1-2 43-61 4.2000 |
| |
De Petrocellis, Melck, Palmisano, Bisogno, Laezza, Bifulco, Di Marzo:
"The endogenous cannabinoid anandamide inhibits human breast cancer
cell proliferation" Chem Phys Lipids 108,1-2 191-209 11.2000 |
| |
Chan, Sills, Braun, Haseman, Bucher: "Toxicity and carcinogenicity
of delta 9-tetrahydrocannabinol in Fischer rats and B6C3F1 mice"
J Mol Med 78,11 613-625 2001 THC nicht karzinogen in Mäusen.. |
| |
Novak, Zitterl-Eglseer, Deans, Franz: "Essential oils of different
cultivars of Cannabis sativa L. and their antimicrobial activity"
Flavour Fragr J 16,4 259-262 2001 |
| |
Sánchez, de Ceballos, del Pulgar, Rueda, Corbacho, Velasco,
Galve-Roperh, Huffman, y Cajal, Guzman: "Inhibition of glioma growth
in vivo by selective activation of the CB(2) cannabinoid receptor"
Cancer Res 61,15 5784-5789 1.8.2001 |
| |
Recht, Salmonsen, Rosetti, Jang, Pipia, Kubiatowski, Karim, Ross,
Zurier, Litofsky, Burstein: "Antitumor effects of ajulemic acid
(CT3), a synthetic non-psychoactive cannabinoid" Biochem J 358,Pt
1 249-55 15.8.2001 |
| |
Parolaro, Massi, Rubino, Monti: "Endocannabinoids in the immune
system and cancer" J Pharmacol Exp Ther 299,3 951-959 12.2001 |
| |
White, Munson, Munson, Carchman: "Effects of delta9-tetrahydrocannabinol
in Lewis lung adenocarcinoma cells in tissue culture" Prostaglandins
Leukot Essent Fatty Acids 66,2-3 319-332 2.2002 |
| |
McKallip, Lombard, Fisher, Martin, Ryu, Grant, Nagarkatti, Nagarkatti:
"Targeting CB2 cannabinoid receptors as a novel therapy to treat
malignant lymphoblastic disease" Blood 100,2 627-634 15.7.2002 |
| |
US-Patent 6630507: Cannabioide als Antioxidanz und Nervenschutz. Hampson,
Axelrod, Grimaldi US-Gesundheitsministerium 21.4.1999 -> 7.10.2003
nützlich bei Schlaganfall, Traumata, Alzheimer, Parkinson, HIV,
Epilepsie.. |
| |
Casanova, Blázquez, Martínez-Palacio, Villanueva, Fernández-Aceñero,
Huffman, Jorcano, Guzman: "Inhibition of skin tumor growth and
angiogenesis in vivo by activation of cannabinoid receptors" J
Clin Invest 111,1 43-50 1.2003 |
| |
Blázquez, Casanova, Planas, Gómez Del Pulgar, Villanueva,
Fernández-Aceñero, Aragonés, Huffman, Jorcano,
Guzman: "Inhibition of tumor angiogenesis by cannabinoids"
FASEB J 17,3 529-531 3.2003 |
| |
Mimeault, Pommery, Wattez, Bailly, Hénichart: "Anti-proliferative
and apoptotic effects of anandamide in human prostatic cancer cell lines:
implication of epidermal growth factor receptor down-regulation and
ceramide production" Prostate 56,1 1-12 15.6.2003 |
| |
Guzman: "Cannabinoids: potential anticancer agents" Nat
Rev Cancer 3,10 745-755 10.2003 |
| |
Massi, Vaccani, Ceruti, Colombo, Abbracchio, Parolaro: "Antitumor
effects of cannabidiol, a nonpsychoactive cannabinoid, on human glioma
cell lines" J Pharmacol Exp Ther 308,3 838-845 3.2004 Cannabis
gg. Gliome.. |
| |
Blázquez, González-Feria, Alvarez, Haro, Casanova, Guzman:
"Cannabinoids inhibit the vascular endothelial growth factor pathway
in gliomas" Cancer Res 64,16 5617-5623 15.8.2004 |
| |
Velasco, Galve-Roperh, Sánchez, Blázquez, Guzman: "Hypothesis:
cannabinoid therapy for the treatment of gliomas?" Neuropharmacology
47,3 315-323 9.2004 Cannabis gg. Gliome wie Glioblastoma multiforme
oder grade IV astrocytoma.. bösartige Hirntumore.. |
| |
Powles, Poele, Shamash, Chaplin, Propper, Joel, Oliver, Liu: "Cannabis-induced
cytotoxicity in leukemic cell lines: the role of the cannabinoid receptors
and the MAPK pathway" Blood 105,3 1214-1221 1.2.2005 |
| |
Sarfaraz, Afaq, Adhami, Mukhtar: "Cannabinoid receptor as a novel
target for the treatment of prostate cancer" Cancer Res 65,5 1635-1641
1.3.2005 Cannabis als Zellwachstumshemmer, antientzündlich, Tumorrückbildung.. |
| |
McAllister, Chan, Taft, Luu, Abood, Moore, Aldape, Yount: "Cannabinoids
selectively inhibit proliferation and induce death of cultured human
glioblastoma multiforme cells" J Neurooncol 74,1 31-40 8.2005 |
| |
Kogan: "Cannabinoids and cancer" Mini Rev Med Chem 5,10
941-952 10.2005 |
| |
Patsos, Hicks, Dobson, Greenhough, Woodman, Lane, Williams, Paraskeva:
"The endogenous cannabinoid, anandamide, induces cell death in
colorectal carcinoma cells: a possible role for cyclooxygenase 2"
Gut 54,12 1741-1750 12.2005 |
| |
McKallip, Jia, Schlomer, Warren, Nagarkatti, Nagarkatti: "Cannabidiol-induced
apoptosis in human leukemia cells: a novel role of cannabidiol in the
regulation of p22 phox and Nox4 expression" Mol Pharmacol 70 897-908
2006 |
| |
Carracedo, Lorente, Egia, Blázquez, García, Giroux,
Malicet, Villuendas, Gironella, González-Feria, Piris, Iovanna,
Guzman, Velasco: "The stress-regulated protein p8 mediates cannabinoid-induced
apoptosis of tumor cells" Cancer Cell 9,4 301-312 4.2006 |
| |
Carracedo, Gironella, Lorente, Garcia, Guzman, Velasco, Iovanna: "Cannabinoids
induce apoptosis of pancreatic tumor cells via endoplasmic reticulum
stress-related genes" Cancer Res 66,13 6748-6755 1.7.2006 |
| |
Caffarel, Sarrió, Palacios, Guzman, Sánchez: "Delta9-tetrahydrocannabinol
inhibits cell cycle progression in human breast cancer cells through
Cdc2 regulation" Cancer Res 66,13 6615-6621 1.7.2006 |
| |
Guzman, Duarte, Blázquez, Ravina, Rosa, Galve-Roperh, Sánchez,
Velasco, González-Feria: "A pilot clinical study of Delta9-tetrahydrocannabinol
in patients with recurrent glioblastoma multiforme" Br J Cancer
95,2 197-203 17.7.2006 |
| |
Afaq, Sarfaraz, Syed, Khan, Malik, Bailey, Mukhtar: "Cannabinoid
receptors as a target for therapy of ovarian cancer" Proc Am Assoc
Cancer Res 47 2006 |
| |
Ligresti, Moriello, Starowicz, Matias, Pisanti, De Petrocellis, Laezza,
Portella, Bifulco, Di Marzo: "Antitumor activity of plant cannabinoids
with emphasis on the effect of cannabidiol on human breast carcinoma"
J Pharmacol Exp Ther 318,3 1375-1387 9.2006 THC erfolgreich gegen Krebs.. |
| |
Gustafsson, Christensson, Sander, Flygare: "Cannabinoid receptor-mediated
apoptosis induced by R(+)-methanandamide and Win55,212-2 is associated
with ceramide accumulation and p38 activation in mantle cell lymphoma"
Mol Pharmacol 70,5 1612-1620 11.2006 |
| |
Calatozzolo, Salmaggi, Pollo, Sciacca, Lorenzetti, Franzini, Boiardi,
Broggi, Marras: "Expression of cannabinoid receptors and neurotrophins
in human gliomas" Neurol Sci 28,6 304-310 12.2007 |
| |
McAllister, Christian, Horowitz, Garcia, Desprez: "Cannabidiol
as a novel inhibitor of Id-1 gene expression in aggressive breast cancer
cells" Mol Cancer Ther 6,11 2921-2927 11.2007 |
| |
Galanti, Fisher, Kventsel, Shoham, Gallily, Mechoulam, Lavie, Amariglio,
Rechavi, Toren: "Delta 9-tetrahydrocannabinol inhibits cell cycle
progression by downregulation of E2F1 in human glioblastoma multiforme
cells" Acta Oncol 47,6 1062-1070 2008 |
| |
Ramer, Hinz: "Inhibition of cancer cell invasion by cannabinoids
via increased expression of tissue inhibitor of matrix metalloproteinases-1"
J Natl Cancer Inst 100,1 59-69 2.1.2008 |
| |
Sarfaraz, Adhami, Syed, Afaq, Mukhtar: "Cannabinoids for cancer
treatment: progress and promise" Cancer Res 68,2 339-342 15.1.2008 |
| |
Michalski, Oti, Erkan, Sauliunaite, Bergmann, Pacher, Batkai, Müller,
Giese, Friess, Kleeff: "Cannabinoids in pancreatic cancer: correlation
with survival and pain" Int J Cancer 122,4 742-750 15.2.2008 gute
Bilder.. |
| |
Parolaro, Massi: "Cannabinoids as a potential new drug therapy
for the treatment of gliomas" Expert Rev Neurotherapeutics 8,1
37-49 1.2008 |
| |
Preet, Ganju, Groopman: "Delta9-Tetrahydrocannabinol inhibits
epithelial growth factor-induced lung cancer cell migration in vitro
as well as its growth and metastasis in vivo" Oncogene 27,3 339-346
10.1.2008 |
| |
Appendino, Gibbons, Giana, Pagani, Grassi, Stavri, Smith, Rahman:
"Antibacterial cannabinoids from Cannabis sativa: a structure-activity
study" J Nat Prod 71,8 1427-1430 8.2008 |
| |
Gustafsson, Wang, Severa, Eriksson, Kimby, Merup, Christensson, Flygare,
Sander: "Expression of cannabinoid receptors type 1 and type 2
in non-Hodgkin lymphoma: growth inhibition by receptor activation"
Int J Cancer 123,5 1025-1033 1.9.2008 |
| |
Liu, Scott, Shamash, Joel, Powles: "Enhancing the in vitro cytotoxic
activity of Delta9-tetrahydrocannabinol in leukemic cells through a
combinatorial approach" Leuk Lymphoma 49,9 1800-1809 9.2008 |
| |
Radwan, Elsohly, Slade, Ahmed, Khan, Ross: "Biologically active
cannabinoids from high-potency Cannabis sativa" J Nat Prod 72,5
906-911 2009 |
| |
Salazar, Carracedo, Salanueva, Hernández-Tiedra, Lorente, Egia,
Vázquez, Blázquez, Torres, García, Nowak, Fimia,
Piacentini, Cecconi, Pandolfi, González-Feria, Iovanna, Guzman,
Boya, Velasco: "Cannabinoid action induces autophagy-mediated cell
death through stimulation of ER stress in human glioma cells" J
Clin Invest 119,5 1359-1372 1.5.2009 THC erfolgreich gg.Krebs.. |
| |
Izzo, Camilleri: "Cannabinoids in intestinal inflammation and
cancer" Pharmacol Res 60,2 117-125 8.2009 |
| |
Marcu, Christian, Lau, Zielinski, Horowitz, Lee, Pakdel, Allison,
Limbad, Moore, Yount, Desprez, McAllister: "Cannabidiol enhances
the inhibitory effects of delta9-tetrahydrocannabinol on human glioblastoma
cell proliferation and survival" Mol Cancer Ther 9,1 180-189 6.1.2010
THC als Universalmittel gg. Krebs.. zur Behandlung von Glioblastomen.. |
| |
Nissen, Zatta, Stefanini et al: "Characterization and antimicrobial
activity of essential oils of industrial hemp varieties (Cannabis sativa
L.)" Fitoterapia 81,5 413-419 2010 |
| |
Whyte, Al-Hammadi, Balhaj, Brown, Penefsky, Souid: "Cannabinoids
inhibit cellular respiration of human oral cancer cells" Pharmacology
85,6 328-335 2010 |
| |
Reiss: "Cannabinoids and viral infections" Pharmaceuticals
(Basel) 3,6 1873-1886 9.6.2010 |
| |
Ramer, Merkord, Rohde, Hinz: "Cannabidiol inhibits cancer cell
invasion via upregulation of tissue inhibitor of matrix metalloproteinases-1"
Biochem Pharmacol 79,7 955-966 1.4.2010 |
| |
Leelawat, Leelawat, Narong, Matangkasombut: "The dual effects
of delta(9)-tetrahydrocannabinol on cholangiocarcinoma cells: anti-invasion
activity at low concentration and apoptosis induction at high concentration"
Cancer Invest 28,4 357-363 5.2010 |
| |
Caffarel, Andradas, Mira, Pérez-Gómez, Cerutti, Moreno-Bueno,
Flores, García-Real, Palacios, Mañes, Guzman, Sánchez:
"Cannabinoids reduce ErbB2-driven breast cancer progression through
Akt inhibition" Mol Cancer 9 196 22.7.2010 |
| |
Torres, Lorente, Rodríguez-Fornés, Hernández-Tiedra,
Salazar, García-Taboada, Barcia, Guzman, Velasco: "A combined
preclinical therapy of cannabinoids and temozolomide against glioma"
Mol Cancer Ther 10,1 90-103 1.2011 Glioblastoma multiforme.. |
| |
Preet, Qamri, Nasser, Prasad, Shilo, Zou, Groopman, Ganju: "Cannabinoid
receptors, CB1 and CB2, as novel targets for inhibition of non-small
cell lung cancer growth and metastasis" Cancer Prev Res (Phila)
4,1 65-75 1.2011 |
| |
Foroughi, Hendson, Sargent, Steinbok: "Spontaneous regression
of septum pellucidum/forniceal pilocytic astrocytomas - possible role
of Cannabis inhalation" Childs Nerv Syst 27,4 671-679 4.2011 |
| |
Vara, Salazar, Olea-Herrero, Guzman, Velasco, Díaz-Laviada:
"Anti-tumoral action of cannabinoids on hepatocellular carcinoma:
role of AMPK-dependent activation of autophagy" Cell Death Differ
18,7 1099-1111 7.2011 |
| |
McAllister, Murase, Christian, Lau, Zielinski, Allison, Almanza, Pakdel,
Lee, Limbad, Liu, Debs, Moore, Desprez: "Pathways mediating the
effects of cannabidiol on the reduction of breast cancer cell proliferation,
invasion, and metastasis" Breast Cancer Res Treat 129,1 37-47 8.2011
Brustkrebs.. |
| |
"Boy, two, with brain cancer is 'cured' after secretly being
fed medical marijuana by his father" Daily mail online 4.5.2011
 |
| |
Ali, Almagboul, Khogali, Gergeir: "Antimicrobial activity of
Cannabis sativa L" Chin Med 3,1 61-64 2012 |
| |
Lone, Lone: "Extraction of cannabinoids from Cannabis sativa
L plant and its potential antimicrobial activity" Univ J Med Dent
1,4 51-55 2012 |
| |
Ramos, Bianco: "The role of cannabinoids in prostate cancer:
Basic science perspective and potential clinical applications"
Indian J Urol 28,1 9-14 2012 |
| |
Ramer, Bublitz, Freimuth, Merkord, Rohde, Haustein, Borchert, Schmuhl,
Linnebacher, Hinz: "Cannabidiol inhibits lung cancer cell invasion
and metastasis via intercellular adhesion molecule-1" FASEB J 26,4
1535-1548 4.2012 |
| |
Aviello, Romano, Borrelli, Capasso, Gallo, Piscitelli, Di Marzo, Izzo:
"Chemopreventive effect of the non-psychotropic phytocannabinoid
cannabidiol on experimental colon cancer" J Mol Med (Berl) 90,8
925-934 8.2012 |
| |
Caffarel, Andradas, Pérez-Gómez, Guzman, Sánchez:
"Cannabinoids: a new hope for breast cancer therapy?" Cancer
Treat Rev 38,7 911-918 11.2012 |
| |
De Petrocellis, Ligresti, Moriello, Iappelli, Verde, Stott, Cristino,
Orlando, Di Marzo: "Non-THC cannabinoids inhibit prostate carcinoma
growth in vitro and in vivo: pro-apoptotic effects and underlying mechanisms"
Br J Pharmacol 168,1 79-102 1.2013 |
| |
Harrison: "Marijuana may lower bladder cancer risk" American
Urological Association (AUA) 2013 Annual Scientific Meeting 10.5.2013
Studie Thomas, Kaiser Permanente.. |
| |
Thomas, Wallner, Quinn, Slezak, Chien, Jacobsen: "Association
between cannabis use and risk of bladder cancer: Results from the California
Men's Health Study" Am Urological Assoc Ann Meeting, San Diego,
CA 4-8.5.2013 Abstract 1290.. 45% weniger Blasenkrebs.. |
| |
Scott, Shah, Dalgleish, Liu: "Enhancing the activity of cannabidiol
and other cannabinoids in vitro through modifications to drug combinations
and treatment schedules" Anticancer Res 33,10 4373-4380 10.2013 |
| |
Singh, Bali: "Cannabis extract treatment for terminal acute lymphoblastic
leukemia with a Philadelphia chromosome mutation" Case Rep Oncol
6,3 585-592 28.11.2013 Hanfölbehandlung.. |
| |
Monika, Kaur: "Antimicrobial analysis of leaves of Cannabis sativa"
J Sci 4 123-127 2014 |
| |
Khan, Warner, Wang: "Antibacterial properties of hemp and other
natural fibre plants: a review" Bio Res 9,2 3642-3659 2014 |
| |
Armentano: "Emerging clinical applications for cannabis and cannabinoids.
A review of the recent scientific literature" 6. Fassung 31.1.2014 |
| |
Rocha, Júnior, Stefano, da Silveira: "Systematic review
of the literature on clinical and experimental trials on the antitumor
effects of cannabinoids in gliomas" J Neurooncol 116,1 11-24 1.2014 |
| |
Naveed, Khan, Ali, Hassan, Ali, Din, Hassan, Tabassum, Saqib, Majid,
Rehman: "In vitro antibacterial activity of Cannabis sativa leaf
extracts to some selective pathogenicbacterial strains" Int J Biosci
4,4 65-70 20.2.2014 antibakterielle Hemmung von Cannabis-Blattextrakt
gg. Staphylococcus aureus (24.1mm), E. coli (22.2mm), Pseudomunas aeruginosa
(10.3mm), Enterococcus faecalis (18.1mm).. |
| |
Isahq, Afridi, Ali, Hussain, Ahmad, Kanwal: "Proximate composition,
phytochemical screening, GC-MS studies of biologically active cannabinoids
and antimicrobial activities of Cannabis indica" Asian Pac J Trop
Dis 5,11 897-902 2015 |
| |
Subramenium, Vijayakumar, Pandian: "Limonene inhibits streptococcal
biofilm formation by targeting surface-associated virulence factors"
J Med Microbiol 64,8 879-890 2015 |
| |
McAllister, Soroceanu, Desprez: "The antitumor activity of plant-derived
non-psychoactive cannabinoids" J Neuroimmune Pharmacol 10,2 255-267
6.2015 Cannabis gg. Krebs.. |
| |
Su, Ho: "Composition of the leaf essential oil of Phoebe formosana
from Taiwan and its in vitro cytotoxic, antibacterial, and antifungal
activities" Nat Prod Commun 11,6 845-848 2016 |
| |
Maida, Daeninck: "A user's guide to cannabinoid therapies in
oncology" Curr Oncol 23,6 398-406 12.2016 Cannabis gg. Schmerzen,
Übelkeit, Erbrechen, Krebs, als Appetitanreger.. |
| |
Thiele: "Cannabis. Verkannte Heilpflanze. Die Wunderpflanze?"
Revue 42 15-20 19.10.2016 Hanf gg. Multiple Sklerose MS, Krebs, Hirntumor,
ADHS.. |
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Hernández-Cervantes, Méndez-Díaz, Prospéro-García,
Morales-Montor: "Immunoregulatory role of Cannabinoids during infectious
disease" Neuroimmunomodulation 24 183-199 2017 |
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Marini, Magi, Ferretti et al: "Attenuation of Listeria monocytogenes
virulence by Cannabis sativa L. essential oil" Front Cell Infect
Microbiol 8 293 2018 |
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Chakraborty, Afaq, Singh, Majumdar: "Antimicrobial activity of
Cannabis sativa, Thuja orientalis and Psidium guajava leaf extracts
against methicillin-resistant Staphylococcus aureus" J Integr Med
16,5 350-357 9.2018 MRSA.. |
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Iseppi, Brighenti, Licata et al: "Chemical characterization and
evaluation of the antibacterial activity of essential oils from fibre-type
Cannabis sativa L. (Hemp)" Molecules 24,12 2302 2019 |
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Shapira, Berman, Futoran, Guberman, Meiri: "Tandem mass spectrometric
quantification of 93 terpenoids in Cannabis using static headspace injections"
Anal Chem 91,17 11425-11432 2019 |
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Frassinetti, Gabriele, Moccia, Longo, Di Gioia: "Antimicrobial
and antibiofilm activity of Cannabis sativa L. seeds extract against
Staphylococcus aureus and growth effects on probiotic Lactobacillus
spp." LWT 124 109149 2020 |
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Stahl, Vasudevan: "Comparison of efficacy of cannabinoids versus
commercial oral care products in reducing bacterial content from dental
plaque: a preliminary observation" Cureus 12,1 e6809 2020 |
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Farha, El-Halfawy, Gale, MacNair, Carfrae, Zhang, Jentsch, Magolan,
Brown: "Uncovering the hidden antibiotic potential of cannabis"
ACS Infect Dis 6,3 338-346 13.3.2020 |
| |
Klahn: "Cannabinoids - promising antimicrobial drugs or intoxicants
with benefits?" Antibiotics (Basel) 9,6 297 2.6.2020 Cannabinoide
mit stark antimikrobieller Aktivität vor allem gg. Gram-positive
Bakterien incl. MRSA.. Appetitstimulation, schmerzlindernd, gg. grünen
Star, gg. Übelkeit, gg. Entzündung, gg. Ängste, gg. Psychosen,
gg. Diabetes, Nervenschutz, gg. Psorisasis, gg. Ischämie, Gefäßentspannend,
gg. Epilepsie, gg. Spasmen, Knochenaufbau, Antikrebs.. antimicrobial
(Mikroben), antibakteriell (Bakterien), anti-MRSA, antiprotozoal (Protozoen),
antiplasmodial (Plasmodien), antimycotic (Pilze). antileishmanial (L.
donovani), antibiofilm (Biofilm), anti-persister, anti-inflammatory
(Entzündung), antiglaucoma (Grüner Star), antiepileptic (Epilspsie),
antispasmolytic (Spasmen), antidiabetic (Diabetes), antitumor (Krebs),
anti-nausea (Übelkeit).. |
| |
Vasudevan, Stahl: "Cannabinoids infused mouthwash products are
as effective as chlorhexidine on inhibition of total-culturable bacterial
content in dental plaque samples" J Cannabis Res 2,1 20 23.6.2020 |
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Martinenghi, Jønsson, Lund, Jenssen: "Isolation, purification,
and antimicrobial characterization of cannabidiolic acid and cannabidiol
from Cannabis sativa L." Biomolecules 10,6 900 12.6.2020 CBD hemmt
Gram-positive Bakterien wie Staph. aureus, Staphylococcus epidermidis.. |
| |
Karas, Wong, Paulin, Mazeh, Hussein, Li, Velkov: "The antimicrobial
activity of cannabinoids" Antibiotics (Basel) 9,7 406 13.7.2020 |
| |
Galletta, Reekie, Nagalingam, Bottomley, Harry, Kassiou, Triccas:
"Rapid antibacterial activity of cannabichromenic acid against
methicillin-resistant Staphylococcus aureus" Antibiotics (Basel)
9,8 523 16.8.2020 MRSA.. |
| |
Blaskovich, Kavanagh, Elliott, Zhang, Ramu, Amado, Lowe, Hinton, Pham,
Zuegg, Beare, Quach, Sharp, Pogliano, Rogers, Lyras, Tan, West, Crawford,
Peterson, Callahan, Thurn: "The antimicrobial potential of cannabidiol"
Commun Biol 4,1 7 19.1.2021 Cannabidiol gg. Biofilme, Clostridioides
difficile, Cutibacterium acnes, Enterococcus faecium, Enterococcus faecalis,
Legionella pneumophila, Moraxella catarrhalis, MRSA, Neisseria gonorrhoeae,
Neisseria meningitidis, Staphylococcus aureus, Staphylococcus epidermidis,
Streptococcus pneumoniae, Streptococcus pyogenes.. |
| |
Volmar, Cheng, Alenezi, Richter, Haug, Hassan, Goldberg, Li, Hou,
Herold-Mende, Maire, Lamszus, Flüh, Held-Feindt, Gargiulo, Topping,
Schilling, Saur, Schneider, Synowitz, Schick, Kälin, Glass: "Cannabidiol
converts NFkB into a tumor suppressor in glioblastoma with defined antioxidative
properties" Neuro Oncol noab095 17.4.2021 Krebs.. |
| |
Schofs, Sparo, Bruni: "The antimicrobial effect behind Cannabis
sativa" Pharmacol Res Perspect 9,2 e00761 4.2021 antibakterielle
Wirkung gg. Acinetobacter calcoaceticus, Aeromonas hydrophyla, Bacillus
anthracis, B. cereus, Bacillus pumilus, Bacillus subtilis, Bacillus
spp., Beneckea natriegens, Brevibacterium linens, Brochothrix thermosphacta,
Clostridium perfringens, Clostridium spp., Corynebacterium cutis, Corynebacterium
diphtheriae, Cryptococcus neoformans, Diplococcus pneumoniae, E. coli,
E. coli ATCC 25922, E. coli VCS257, Enterobacter aerogenes ATCC, Enterococcus faecalis ATCC 29212,
Enterococcus faecium, Enterococcus hirae, Enterococcus spp., Enterococcus,
Erysipelothrix rhusiopathiae, Flavobacterium suaveolens, Helicobacter
pylori, Klebsiella pneumoniae, Listeria monocytogenes, Methicillin Resistant
S. aureus MRSA, MRSE, MSSA, Micrococcus flavus, Micrococcus luteus,
Mycobacterium smegmatis, Mycobacterium tuberculosis, P. aeruginosa,
Proteus mirabilis, Salmonella enterica ser. Typhimurium ATCC 14028,
Staphylococcus spp., S. aureus ATCC 25923, S. aureus ATCC 29213, S.
aureus subsp. aureus Rosenbach, Staphylococcus aureus, Streptococcus
alpha haemolyticus, Streptococcus beta haemolyticus, Streptococcus mutans,
Streptococcus salivarius subsp. thermophilus, S. epidermidis CA71, S.
epidermidis ATCC51625, Streptococcus spp., S. typhimurium ATCC 14028,
Trichophyton mentagrophytes, Vibro cholerae, Vibrio harveyi, Yersinia
enterocolitica..
Gram-negative Bakterien P. vulgaris, Bordetella bronchiseptica.. Pilze
Aspergillus niger, Aspergillus oryzae, Aspergillus parasiticus, Candida
albicans, Hefe..
Parasiten Leishmania donovani.. |
| |
Nguyen, Yang, Nicolaescu, Best, Ohtsuki, Chen, Friesen, Drayman,
Mohamed, Dann, Silva, Gula, Jones, Millis, Dickinson, Tay, Oakes, Pauli,
Meltzer, Randall, Rosner: "Cannabidiol inhibits SARS-CoV-2 replication
and promotes the host innate immune response" BioRxiv 10.3.2021 |
